Description
Product Characteristics: AAT 5 antibody, AAT5 antibody, Activin A receptor type II like kinase 53 kDa antibody, Activin A receptor type II like kinase antibody, Activin A receptor type II like kinase, 53kD antibody, Activin A receptor type II like protein kinase of 53kD antibody, activin A receptor type II-like kinase, 53 kDa antibody, activin A receptor type II-like protein kinase of 53kD antibody, Activin receptor like kinase 5 antibody, Activin receptor-like kinase 5 antibody, ACVRLK 4 antibody, ACVRLK4 antibody, ALK 5 antibody, ALK-5 antibody, ALK5 antibody, LDS1A antibody, LDS2A antibody, MSSE antibody, Serine/threonine protein kinase receptor R4 antibody, Serine/threonine-protein kinase receptor R4 antibody, SKR 4 antibody, SKR4 antibody, TbetaR I antibody, TbetaR-I antibody, TGF beta receptor type 1 antibody, TGF beta receptor type I antibody, TGF beta type I receptor antibody, TGF-beta receptor type I antibody, TGF-beta receptor type-1 antibody, TGF-beta type I receptor antibody, TGFBR 1 antibody, TGFBR1 antibody, TGFBR1 protein antibody, TGFR 1 antibody, TGFR-1 antibody, TGFR1 antibody, TGFR1_HUMAN antibody, Transforming growth factor beta receptor 1 antibody, Transforming growth factor beta receptor I (activin A receptor type II like kinase, 53kD) antibody, Transforming growth factor beta receptor I antibody, transforming growth factor, beta receptor 1 antibody, transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) antibody, Transforming growth factor-beta receptor type I antibody
Target Information: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]